I just downloaded the software today. My first attempt to install worked fine, but then it suggested I install Update 3. That failed to install.
Repairing the existing install didn't work, so I asked it to uninstall. Now all attempts to install fail here:
(ugh, copy doesn't work so I get to transcribe this by hand)
Error message: An error occured [sic] during the installation of assembly component 844EFBA7-1C24-93B2-A01F-C8B3B9A1E18E. HRESULT: 0x80073715
Error code: 1603
File name: amplxe_msvcrt_x64.msi
I tried full installs, minimal installs, etc, they all fail here.
Windows 10 Enterprise Version 1703, 64 bit OS.