I'm using amplxe_cl on FC14 on a new machine. I know, it's not officially supported :-(
Installation, building kernel module.... everything went fine. There seems to be no problems during sampling, but in the post processing:
Using result path `/home/heinecke/Documents/Projects/....'
Executing actions 33 % Resolving information for `libc-2.12.90.so'
From this point no further working of amplxe_cl can be identified (with update 1). The initial release crashed with a segmentation fault. I also have a machine running FC13 and there are no problems.