I posted something like this on the Vtune forums, but it is mainly addressed to the itanium users.
I have not been able to get the optimization report to work for the last 2 years, I have tried everything I could find on the web and so far have never been able to get it to work. Has anyone out there running on an itanium been able to get this report to work? I think it has something to do with the environment, but I am not positive. No errors are thrown, so I really have no concrete place to start looking for the issue.
I realize this post is vague, but I was just hoping to find someone that has success using this tool. Besides this issue, Vtune has behaved well for me and has been a great tool to have.